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Chronic diseases present secondary effects like inflammation and chronic pain. The cause of the pain may be due to headaches, muscle spasticity/contractions, and joint complications. There are independent causes, however, of such difficulties.

Opioids act on the nervous system to reduce pain. However, they exhibit adverse addictive and side effects. As a result, emphasis has shifted to alternative options like herbal medicines. 

Cannabis comprises THC and CBD compounds, which is one reason cannabis reduces pain. Although cannabis compounds relieve pain, federal laws are in place to regulate cannabis use, and it is legal in some countries and illegal in others. 

Therefore, its use either for medicinal or recreational purposes is subject to the laws of the land.

The concept of pain

There is justifiable research that associates cannabis and pain management. Notably, there are different types of pain. Bone pain involves bones in the body or a specific region, possibly due to chronic illnesses like cancer or joint complications.

Soft tissue pain results from inflammation of damaged tissues and body organs – nerve pain results from a damaged nervous system. Total pain includes psychological, physical, and social discomfort.

The application of cannabis compounds in pain management involves a series of actions on the body system. The compounds act on the cannabinoid system to control and relieve pain in the target organs. The interactions of cannabis compounds on stimuli and receptors clearly show why cannabis reduces pain.

How cannabis compounds act on nociceptors

Cannabis compounds regulate pain stimuli on the nociceptors that help detect pain in the body, while cannabinoids help control pain. During incidences of chronic inflammation, cannabinoids inhibit the secretion of inflammatory factors, thus reducing inflammation and pain.

Cannabis compounds work on the nervous system to interrupt how receptors receive pain stimuli. By so doing, it produces opioid effects. The cannabis compounds additionally act on the endocannabinoid system to regulate pain.

Terpenes, adenosine, serotonin & vanilloid receptors in chronic pain management

There are a variety of reasons why cannabis reduces pain through its interaction with system receptors. Terpenoids work the same way as cannabinoids. Moreover, they deliver both pain-relieving and anti-inflammatory properties to the target organ. The result is reduced pain. 

Cannabis actively interacts with serotonin receptors to produce pain-relieving and treatment effects. Adenosine receptors are responsible for producing glutamate and dopamine neurotransmitters used to eliminate nerve pain. CBD works by playing an inhibitory role to vanilloid receptors accountable for inflammation. Click to buy weed online.


Cannabis compounds produce relaxation and sensation effects; therefore, this is one of the reasons why cannabis reduces pain. Cannabis can be used in different forms, yielding different results. Cannabis use in pain management is either through edibles, smoking, sprays, or topical application. Medications of cannabis consumption to aid pain management differ significantly, and so does the dose.